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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A5
All Species:
23.33
Human Site:
S622
Identified Species:
46.67
UniProt:
Q9H2X9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2X9
NP_001128243.1
1139
126184
S622
R
Y
Y
H
W
T
L
S
F
L
G
M
S
L
C
Chimpanzee
Pan troglodytes
XP_001173480
1150
127612
L666
L
A
C
A
L
Q
T
L
L
R
T
P
N
W
R
Rhesus Macaque
Macaca mulatta
XP_001104798
1116
123517
S599
R
Y
Y
H
W
T
L
S
F
L
G
M
S
L
C
Dog
Lupus familis
XP_543029
1042
114973
L574
M
C
Y
M
F
V
N
L
A
C
A
V
Q
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91V14
1138
126252
S622
R
Y
Y
H
W
T
L
S
F
L
G
M
S
L
C
Rat
Rattus norvegicus
Q63633
1139
126228
S622
R
Y
Y
H
W
T
L
S
F
L
G
M
S
L
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506148
1141
126778
S636
K
Y
Y
H
W
T
L
S
F
L
G
M
S
L
C
Chicken
Gallus gallus
NP_001006371
1125
125222
S616
K
Y
Y
H
W
T
L
S
F
L
G
M
S
L
C
Frog
Xenopus laevis
Q0VGW6
899
98326
A431
V
T
V
F
Y
L
I
A
Y
A
A
I
D
L
A
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
Y431
A
G
I
V
T
V
F
Y
L
L
A
Y
A
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
G552
L
M
T
L
S
L
L
G
A
A
L
C
F
F
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38329
1120
123980
G628
V
F
I
G
S
G
L
G
G
M
K
P
N
I
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
96.1
88
N.A.
98.2
98.2
N.A.
72.1
73
24.6
25.2
N.A.
N.A.
N.A.
35.9
N.A.
Protein Similarity:
100
81
97
89.1
N.A.
98.6
98.8
N.A.
82.9
83.9
42.7
43.1
N.A.
N.A.
N.A.
54.8
N.A.
P-Site Identity:
100
0
100
6.6
N.A.
100
100
N.A.
93.3
93.3
6.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
100
20
N.A.
100
100
N.A.
100
100
40
13.3
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
0
0
9
17
17
25
0
9
9
9
% A
% Cys:
0
9
9
0
0
0
0
0
0
9
0
9
0
0
50
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
9
9
0
9
0
50
0
0
0
9
9
0
% F
% Gly:
0
9
0
9
0
9
0
17
9
0
50
0
0
0
0
% G
% His:
0
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
0
9
0
0
0
0
9
0
9
9
% I
% Lys:
17
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
17
0
0
9
9
17
67
17
17
59
9
0
0
59
9
% L
% Met:
9
9
0
9
0
0
0
0
0
9
0
50
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
17
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% Q
% Arg:
34
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% R
% Ser:
0
0
0
0
17
0
0
50
0
0
0
0
50
0
0
% S
% Thr:
0
9
9
0
9
50
9
0
0
0
9
0
0
9
9
% T
% Val:
17
0
9
9
0
17
0
0
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
50
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
50
59
0
9
0
0
9
9
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _